| 1900 | Merck initiated its business in China through distributing high-purity reagents via the ports of Shanghai, Guangzhou and Tianjin |
| 1935 | E. Merck Co., Ltd. established in Shanghai, supplying a range of pharmaceutical and chemical products |
| 1953 | Agency agreements with Jebsen & Co., Ltd. (HongKong) for selling Merck products in China |
| 1994 | Merck delegates arrived in China |
| 1995 | Merck representative office established in Beijing |
| 1996 | Merck representative office established in Shanghai |
| 1997 | Merck representative office established in Guangzhou |
| 06/1997 | Incorporation of Merck Ltd. (HongKong) |